Bioinformatics is the science of storing, extracting, organizing, analyzing, and interpreting biological sequence data. The course is designed to introduce the most basic concepts and up-to-date developments, methods, and tools used in bioinformatics. Topics include bioinformatics databases, resources at NCBI and EBI, sequence and structure alignment, file formats, analysis of single DNA and protein sequences, BLAST, primer design, function predictions, phylogenetics, and protein structure prediction. Internet laboratory for teaching the databases and data mining tools will be considered.